Bacterial infections are hard to fight. It's not just that there are "superbugs" which resist antibiotics, like MRSA -- it's that the methods for finding effective antibiotics aren't very efficient. However, scientists have developed a technique that harnesses environmental bacteria to find antimicrobial weapons much more quickly. Their approach uses a mix of moistened soil, liquid agar (bacterial culture) and diluted bacterial samples to isolate microbes for study while giving them the natural conditions they need to grow. At least in theory, medical researchers no longer have to limit their antibiotic development to bacteria that survive in lab conditions. If it grows in dirt, it's a candidate.
The team behind the new method has already produced a very promising antibiotic, teixobactin. It not only kills certain kinds of harmful bacteria (namely those with cellular walls, like anthrax and tuberculosis), but makes it difficult for those bugs to evolve resistance. It'll be a while before teixobactin is a practical treatment, and it won't be useful in many other circumstances. But that's almost beside the point -- thanks to the new research technique, it's no longer far fetched to think that humans can stay one step ahead of sickness-inducing organisms.
[Image credit: AP Photo/Kirsty Wigglesworth]
Filed under: Science
Via: National Geographic, Gizmodo
Source: Nature
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